OCRF-funded research project
IDENTIFYING NEW TREATMENT OPTIONS
Institution: Walter & Eliza Hall Institute of Medical Research Lead
Researcher: Dr Holly Barker
Funding Awarded: $150,000
Total Collaborative Funding: $300,000
Funding Collaboration: Cancer Council Victoria
Year/s: 2020-2023
Research Pillar: New & Effective Treatments
Project Description:
Treatment options for ovarian cancer have not significantly changed in over three decades. In this project the team at Walter and Eliza Hall Institute of Medical Research, led by Dr Holly Barker, aim to understand why ovarian cancer, particularly ovarian carcinosarcoma, is such an aggressive cancer.
The researchers have conducted genetic screens and drug screens to identify potential targets, and they will develop organoid models in order to test the most promising drug combinations against their identified targets.
Expected/Achieved Outcomes:
Knowledge Building: The aim is to generate preliminary data that could be translated into a clinical setting, ultimately providing faster outcomes for patients and offering a new option to patients for whom current standard of care therapies are not effective.
Project Status:
The team are currently finalising in vivo studies and validating the most promising drugs with the hope of an upcoming clinical trial for rapid research translation.
Further Details and Publications:
Medical Journal
Elements of this project have been published in medical journals. Read more here.
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