OCRF-FUNDED RESEARCH PROJECT

A NEW RADIO IMAGING AGENT TO GUIDE TARGETED THERAPY FOR EPITHELIAL OVARIAN CANCER

Institution: Mater Research Institute, The University of Queensland

Lead Researcher: Professor John Hooper

Funding Awarded: $60,000

Total Collaborative Funding: $1,250,000

Funding collaboration: Medical Research Future Fund

Year/s: 2020-2024


Project Description:

Professor John Hooper and his team from Mater Research at The University of Queensland is focused on developing agents that can both diagnose and treat epithelial ovarian cancer. The team’s goal is to evaluate a new radio-imaging agent to guide targeted therapy for women who have ovarian cancer, in the first study of its kind in humans. By administering this new agent, the team will attach a tracer to the ovarian cancer cells, which is expected to make detection of the disease easier during radiology scans, similar to what is currently performed with prostate cancer diagnosis. Professor Hooper says the project is the culmination of nearly 20 years of research - all the way from the initial discovery in the lab to being here on the threshold of conducting a clinical trial. The project is a wonderful collaboration of scientists and clinicians from very diverse backgrounds as well as patients and family members who are guiding the team on their journey.

We have also been blessed by the generous support of our country's major ovarian cancer advocacy organisations including the OCRF, ANZGOG and Tour de Cure.

Professor Hooper

Expected/Achieved Outcomes:

Knowledge Building: The aim is to perform a first-in-human study to evaluate the effectiveness of a specific type of theranostic. Theranostics have dual roles in diagnosis and treatment. After the initial study the team will then conduct a preclinical evaluation on several other theranostics that may be effective against ovarian cancer.

Project Status:

This project is currently underway.

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The Ovarian Cancer Research Foundation acknowledges the Traditional Custodians of the lands upon which we work, strive, and learn, the Wurrundjiri Woi wurrung and Bunorung Boon wurrung peoples of the Kulin Nation. We pay our respects to Elders past and present, and extend this respect to all Aboriginal and Torres Strait Islander peoples in Australia and beyond.