Project Description:

This major program of research is focused on analysis of single cells taken from patient tumours and models for a range of cancers. The ACRF awarded $3.5 million towards this Program which focuses on:

• the discovery of triggers that drive cancer development,
• how genetic diversity in cancers affects treatment efficacy,
• and on developing better ways of personalising cancer therapies to conquer the biggest challenges in cancer today

The multidisciplinary collaborative team includes 19 cancer experts and their teams from across the Walter & Eliza Hall Institute, who are accompli shed leaders in breast, ovarian, lung and pancreatic cancers, acute and chronic leukaemias, lymphoma and myeloma. The OCRF is funding salaries of two bioinformaticians who are working on the ovarian cancer aspect of this program. The bioinformaticians, working closely with researchers to maximise the value of new cancer research equipment, operate the sophisticated software required for the new analysis of both single cell genomic data and imaging data from specialist platforms.