Project Description:

There is still little known as to why one patient’s ovarian cancer will remain in the ovaries and respond well to surgery, and another patient’s cancer will rapidly spread throughout the body, leading them to succumb to the disease. Associate Professor Ford’s team’s previous research has identified a group of genes, important in the progression of ovarian cancer, that are potentially linked to the likelihood of survival. They discovered that two receptor molecules, called Ror1 and Ror2, present on the surface of cancer cells can control these genes, raising the possibility of targeting these genes as a new method of treatment. In this project, the team investigated whether targeting these receptors can lead to a promising therapy.