OCRF RESEARCH DIRECTORY

Welcome to the OCRF Research Directory— a directory to help you learn about the OCRF-funded research and researchers that are of most interest to you. You can search by selecting a category from the drop-down below and selecting a ‘tag’ that corresponds to your interest areas. Alternatively, you can use the ‘search bar’ to search the name of a specific researcher or research institute, an ovarian cancer subtype or any keyword to see all relevant articles to your search.

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A new radio-imaging, diagnostic agent to guide targeted therapy for epithelial ovarian cancer

Professor Hooper’s team are testing an innovative formula, developed using a small, safe dose of radioactive particles, which could elevate scanning techniques for more effective ovarian cancer diagnosis and targeted treatment.

Early detection

Treatment

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A new therapy to overcome ovarian cancer recurrence and chemoresistance

Dr Alexander Cole’s team are hoping to develop a nanobody that can treat ovarian cancer by targeting a protein called follistatin.

Treatment

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A new treatment approach for a rare subtype of ovarian cancer: ovarian cancer clear-cell carcinoma

Dr Bolderson’s team are investigating whether targeting a process in DNA damage repair involving lactate could provide the foundations of an effective treatment approach for ovarian cancer clear-cell carcinoma.

Treatment

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A new treatment that increases immune response to ovarian cancer

Professor Brian Gabrielli is trialling a drug combination that he hopes can both effectively treat ovarian cancer and activate the immune system to prevent its recurrence.

Managing recurrence

Treatment

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A novel vaccine for ovarian cancer

The aim of this project is to develop a vaccine that treats ovarian cancer by improving the immune system’s ability to recognise and eliminate cancer cells.

Managing recurrence

Treatment

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Advancing precision therapeutics for low-grade serous ovarian cancer

Professor Anna DeFazio’s team is working to improve treatment options for people with low-grade serous ovarian cancer by identifying new molecular drivers of the disease and developing more targeted therapies.

Treatment

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Advancing treatment approaches for a rare type of ovarian cancer: adult granulosa cell tumours

By focusing on the FOXL2-C134W mutation and its interaction with SMAD proteins present in adult granulosa cell ovarian tumours, Associate Professor Simon Chu’s team hope to develop a new treatment for this disease.

Managing recurrence

Treatment

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Associate Professor Fernando Guimaraes

Associate Professor Fernando Guimaraes specialises in the development of cancer immunotherapies, with a particular focus on natural killer (NK) cells.

Treatment

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Associate Professor Jason Lee

Associate Professor Jason Lee is a leader in cancer epigenetics, running his lab at The University of Queensland’s Frazer Institute.

Managing recurrence

Early detection

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Associate Professor Liz Caldon

Associate Professor Caldon’s research initially specialised in breast cancer, including studies on the similarities between its characteristics and ovarian cancer.

Treatment

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Associate Professor Michelle Hill

Associate Professor Michelle Hill specialises in a field of science call proteomics and examines modifications that impact the way proteins function.

Early detection

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Associate Professor Simon Chu

Associate Professor Simon Chu specialises in research on a very rare form of ovarian cancer, granulosa cell tumours (GCT), which makes up approximately 5-8% of ovarian cancers, with around 100-150 people diagnosed in Australia annually.

Managing recurrence

Early detection

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The Ovarian Cancer Research Foundation acknowledges the Traditional Custodians of the lands upon which we work, strive, and learn, the Wurrundjiri Woi wurrung and Bunorung Boon wurrung peoples of the Kulin Nation. We pay our respects to Elders past and present, and extend this respect to all Aboriginal and Torres Strait Islander peoples in Australia and beyond.